A Study on the Phytochemical and Antimicrobial Properties of Methanol and Methanol/Water Extract of Aerial Part of Phyllantus Niruri

Isah Yinusa, Monday Newman Yakubu, Hassan Kabiru Dahiru

Abstract



ABSTRACT

This work focuses on the phytochemical and antimicrobial screening of the methanol and methanol/water extracts. The phytochemical screening revealed the presence of Carbohydrate, Glycoside, Anthraquinones, Steroidal Triterpenes, Flavonoids, Tannins and Alkaloids while Cardiac glycoside and saponins were found to be absent in the Methanol extract. The Methanol/water extract contain Carbohydrate, Anthraquinones, Cardiac Glycoside, Saponins, Steroidal Triterpenes, Flavonoids, Tannins and Alkaloids. The antimicrobial activities of the extracts were carried out to ascertain which fraction of the extract was more sensitive to the test organism. The methanol extract was found to be sensitive to Staphylococcus aureus, Streptococcus Pyrogenes, Salmonella Typhi, Shigellia Dysenteric, Pseudomonas Aureginosa and Microsperum Canis with high record of zone of inhibition and resistant to Escherichia Coli, Proteus Mirabilis and Trychophyton with low record of zone of inhibition. While the methanol/water extract was found to be sensitive to Streptococcus Pyrogenes, Escherichia Coli, Shigellia Dysenteric, Pseudomonas Aureginosa, and Trychophyton with high record of zone of inhibition while Staphylococcus aureus, Salmonella Typhi, Proteus Mirabilis and Microsperum Canis were resistant to the methanol/water extract with low record of zone of inhibition. Based on the activities of these extracts on the selected microbes their MIC and MBC/MFC were carried out to ascertain their level of activities.

 


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